Cambridge Institute for Medical Research

Foreword

Prof Gillian Griffiths

Message from the Director

The Cambridge Institute for Medical Research (CIMR) was founded in 1998 as a cross-departmental Institute of the University of Cambridge Clinical School. It provides a unique interface between basic and clinical science essential to achieving its major goal of determining and understanding the molecular mechanisms of disease. A distinctive feature of the CIMR is that consistently, since its foundation, over 40% of our 31 Principal Investigators (PIs) have been medically qualified and clinically active, enabling the CIMR to be effective in translating scientific discovery to patient benefit. It currently has an annual grant spend of £21M, 60% funded by awards from the Wellcome Trust.

Over the past 10 years the ability of scientists in the CIMR to make major contributions to understanding the molecular mechanisms of disease has been greatly enhanced by support for our core facilities and Institute activities through Wellcome Trust Strategic Awards.  The success of the CIMR has attracted an unprecedented number of Wellcome funded research fellows with eleven PIs holding personal support awards from the Wellcome Trust (6 Principal Research Fellows and 5 Senior Research Fellows) as well as three Fellows funded by the Medical Research Council.

CIMR has established an international reputation for excellence in the use of genetics and molecular cell biology to understand disease at the cellular level.  We aim to use advances in genomics, cell biology and structural biology to provide a better understanding of the basis of disease, and use recent advances in the pathogenesis and genetics of disease to inform research on fundamental cell biology. 

The Institute will have openings for new group leaders over the next 5 year period and is seeking applications from outstanding clinical and non-clinical candidates whose research interests are within the field of Cellular Medicine.  Although primarily interested in candidates starting their independent research careers, applications at any level will be considered.  Candidates are expected to present strong and creative research proposals enabling them to gain career development and senior fellowships.

Gillian Griffiths, December 2012