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Symeon microscopy image

The mouse lipin 1 is required for lipid droplet biogenesis in differentiating mouse adipocytes. 3T3-L1 cells treated with control siRNA (left panel) or lipin 1 siRNA (right panel). Droplets are labelled in red.
Symeon microscopy image
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A unique partnership between basic and clinical research, aiming to understand the cellular basis of disease






New publications

 

Buss lab (J. Cell Sci. 2017)

Myosin VI function at cardiomyocyte gap junctions.

 

Raymond lab (Nature Genet. 2016)

Identification of a KMT2B-linked movement disorder.

 

Rubinsztein lab (Nature Comm. 2016)

Chaperone inhibition of protein aggregation via autophagy.

 

Ron lab (Nature Struct. Mol. Biol. 2016)

FICD-mediated de-AMPylation of BiP ER chaperone.

 

Huntington lab (Blood 2016)

Engineered serpins for rescue of thrombin generation.

 

Lehner lab (eLife 2016)

Vif targeting of PP2A in HIV infection.