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Symeon schematic

Control of lipid partitioning by the conserved yeast lipin Pah1. Loss of Pah1 results in de-repressed nuclear/ER membrane proliferation (arrows, left panel). Conversely, constitutive activation of Pah1 results in lipid droplet accumulation (arrows, right panel).
Symeon schematic
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A unique partnership between basic and clinical research, aiming to understand the cellular basis of disease






New publications

 

Read lab (PNAS 2017)

Predicting crystal structure success.

 

Maxwell lab (PLoS Genet. 2017)

Altered mitochondrial RNA translation in kidney disease.

 

Rubinsztein lab (Neuron 2017)

Autophagy in neuronal health and disease.

 

Buss lab (PNAS 2017)

Cytoskeletal control by myosin VI motor directionality.

 

Lehner and Weekes labs (eLife 2017)

Mechanisms of NK cell suppression by HCMV.

 

Raymond lab (Nature Genet. 2016)

Identification of a KMT2B-linked movement disorder.