skip to primary navigationskip to content



CIMR building carousel

Research retreat 2011

Wellcome Trust Strategic award logo

Gillian Griffiths

David Rubinsztein

MRC logo

David Ron

Bertie Gottgens

Admin group

Sarah Smith

Jim Huntington

Jennie Blackwell

formal opening

CIMR opening

Planning the institute

CIMR planning b

Robinson lab cake

Robin Antrobus


Linda Wicker

Tony Green

Tony Green in office

Janet Deane

Stefan Marciniak

Folma Buss

Patrick Maxwell

Fiona Karet

Evan Reid

Andres Floto

Paul Luzio

Margaret Robinson

Symeon Siniossoglou

Geoff Woods

autophagy model

Schematic overview of autophagy

Rubinsztein lab

The Rubinsztein lab

Pablo Moreno Cortez

Reiner Schultz

James Nathan

Paul Lehner

Matthew Seaman

Deane lab

Deane lab structure

Deane lab schematic

Folma autophagy

Fiona Gribble

Frank Reimann

David Owen

Katrin Ottersbach

Haploid screen

Joh Todd

2012 Research report

2010 Research report

2008 Research report

Students in the Infection, Immunity and Inflammation PhD programme

Lucy Raymond


spastin for carousel

Autophagy buss lab

galc for carousel

Marciniak imaginal disc

Luzio 2010

Research retreat 2013

Research report 2006

Research report 2004

Research report 2002

Athena SWAN logo

Ken Smith

2014 research report

CIMR happy hour

CIMR happy hour

Stern talk

Huntington in lab

Cambridge Science Festival

John Trowsdale

Peter St George Hyslop

Randy Read

Sadaf Farooqi

Christopher Rudd

Stephen O'Rahilly

Damian Crowther

Sergey Nejentsev

Ken Smith

Retreat poster session

Early CIMR building

PhD students 2103

Festival carousel

Microscopy at festival

Colouring at festival

School visit

Gillian making crystals

Janet at scope

Brian Huntly

Research retreat 2014

CIMR building for facilities

CIMR caption test

CIMR caption new

Alison Schuldt

Trowsdale TAPBPR image

Cytometry team

Cytometry data


Postgraduate Open Day

New publications

Warren lab (Blood 2019)

EFL1 mutations impair eIF6 release to cause Shwachman-Diamond syndrome.

Warren lab (eLife 2019)

Mechanism of completion of peptidyltransferase centre assembly in eukaryotes

Weeke's lab (Cell Reports 2019)

Quantitative Temporal Proteomic Analysis of Vaccinia Virus Infection Reveals Regulation of Histone Deacetylases by an Interferon Antagonist

Rubinsztein lab (Nature Communications 2019)

Felodipine ameliorates neurodegeneration in mice


Sharpe lab (eLife 2019)

The receptor PTPRK selectively dephosphorylates junctional regulators


Ron lab (Nature Comm 2019)

MANF anatagonizes nucleotide exchange by the enodplasmic reticulum chaperone BiP


Robinson lab (Nature Comm. 2018)

AP-4 adaptor in autophagy


Ron lab (Nature Cell Biology)

Single particle trajectories reveal active endoplasmic reticulum luminal flow

Griffiths Lab (Immunity)

PIP5 Kinases Regulate Membrane Phosphoinositide and Actin Composition for Targeted Granule Secretion by Cytotoxic Lymphocytes


Rubinsztein lab (Cell Metabolism)

Leucine metabolism regulates mTORC1


Weekes lab (Cell Host Microbe 2018)

Global analysis of antiviral factors degraded by HCMV

Rubinsztein lab (Nature Comm. 2018)

Autophagy control in contact inhibition


Griffiths lab (Nature Immunol. 2018)

Single cell insights into T cell killing capacity


Larrieu lab (Sci. Signalling 2018)

Transportin-1 targeted in progeria


Siniossoglou lab (Dev. Cell 2018)

A conserved mechanism for membrane phospholipid sensing


Larrieu lab (Nature Comm. 2018)

NAT10 inhibition increases healthspan of HGPS mice


St George-Hyslop lab (Cell 2018)

Phase separation control of FUS in neurodegeneration


Ron lab (J. Biol. Chem. 2018)

Inhibitor sensitivity of the eIF2a phosphatase revisited


Marciniak lab (ASC Nano. 2018)

Measuring microviscosity dynamics inside organelles


Rubinsztein lab (Dev. Cell 2018)

Recycling endosomes as a novel platform for autophagosome formation


Ron and Warren labs (Science 2018)

CryoEM analysis of integrated stress response


Nathan and Lehner labs (EMBO Rep. 2018)

Overlapping E3 ligase function in the ER