Rubinsztein lab
(Nature Communications, 2021)
α-Catenin levels determine direction of YAP/TAZ response to autophagy perturbation
(Nature Chemical Biology, 2021)
VCP/p97 regulates Beclin-1-dependent autophagy initiation
Weekes Lab (Frontiers in Cellular and Infectious Microbiology, 2021)
Rapid Degradation Pathways of Host Proteins During HCMV Infection Revealed by Quantitative Proteomics
Robinson lab (Journal of Cell Biology, 2021)
Rag GTPases and phosphatidylinositol 3-phosphate mediate recruitment of the AP-5/SPG11/SPG15 complex
Rubinsztein lab (Cell Reports, 2020)
mTORC2 Assembly Is Regulated by USP9X-Mediated Deubiquitination of RICTOR
Ron lab (eLife, 2020)
Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes
Ron lab in collaboration with the Ito lab, RIKEN (Molecular Cell, 2020)
ISRIB blunts the Integrated Stress Response by allosterically antagonising the inhibitory effect of phosphorylated eIF2 on eIF2B
Raymond and Reid labs (American Journal of Human Genetics, 2020)
De Novo VPS4A Mutations Cause Multisystem Disease with Abnormal Neurodevelopment
Rayner lab (Nature, 2020)
Red blood cell tension protects against severe malaria in the Dantu blood group
Maxwell lab (Nature Immunology, 2020)
Dynamic regulation of hypoxia-inducible factor-1α activity is essential for normal B cell development
Weekes lab (PNAS, 2020)
Human cytomegalovirus protein pUL36: A dual cell death pathway inhibitor
Woods lab (Cell Reports, 2020)
Human Labor Pain Is Influenced by the Voltage-Gated Potassium Channel KV6.4 Subunit
Deane lab (Nature Communications, 2020)
The receptor PTPRU is a redox sensitive pseudophosphatase
Rubinsztein lab (Nature Communications, 2020)
Leucine regulates autophagy via acetylation of the mTORC1 component raptor
Rubinsztein lab in collaboration with the Goldberg lab, Harvard (PNAS, 2020)
cGMP via PKG activates 26S proteasomes and enhances degradation of proteins, including ones that cause neurodegenerative diseases
Griffiths lab (eLife, 2020)
Stimulation strength controls the rate of initiation but not the molecular organization of TCR-induced signalling
Buss lab (Journal of Cell Science, 2020)
OPTN recruitment to a Golgi-proximal compartment regulates immune signalling and cytokine secretion
Rubinsztein lab (Developmental Cell, 2020)
A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy
Buss lab (Biology of Reproduction, 2020)
Myosin VI maintains the actin-dependent organization of the tubulobulbar complexes required for endocytosis during mouse spermiogenesis
Weekes lab (Scientific Reports, 2020)
Comprehensive cell surface proteomics defines markers of classical, intermediate and non-classical monocytes
Buss lab (Traffic, 2020)
Ultrastructural insights into pathogen clearance by autophagy
Read lab (Acta Crystallographica Section D, 2020)
Measuring and Using Information Gained by Observing Diffraction Data
Read lab (Acta Crystallographica Section D, 2020)
Factors influencing estimates of coordinate error for molecular replacement
© 2021 University of Cambridge
