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Kruppa image 2018

Kruppa image 2018
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Postgraduate Open Day

New publications

Siniossoglou lab (Developmental Cell 2019)

Compartmentalized Synthesis of Triacylglycerol at the Inner Nuclear Membrane Regulates Nuclear Organization

Weekes Lab (Cell Metabolism 2019)

Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation

Warren lab (Blood 2019)

EFL1 mutations impair eIF6 release to cause Shwachman-Diamond syndrome.

Warren lab (eLife 2019)

Mechanism of completion of peptidyltransferase centre assembly in eukaryotes

Weekes lab (Cell Reports 2019)

Quantitative Temporal Proteomic Analysis of Vaccinia Virus Infection Reveals Regulation of Histone Deacetylases by an Interferon Antagonist

Rubinsztein lab (Nature Communications 2019)

Felodipine ameliorates neurodegeneration in mice

Sharpe lab (eLife 2019)

The receptor PTPRK selectively dephosphorylates junctional regulators

Ron lab (Nature Comm 2019)

MANF anatagonizes nucleotide exchange by the enodplasmic reticulum chaperone BiP

Robinson lab (Nature Comm. 2018)

AP-4 adaptor in autophagy

Ron lab (Nature Cell Biology)

Single particle trajectories reveal active endoplasmic reticulum luminal flow

Griffiths Lab (Immunity)

PIP5 Kinases Regulate Membrane Phosphoinositide and Actin Composition for Targeted Granule Secretion by Cytotoxic Lymphocytes

Rubinsztein lab (Cell Metabolism)

Leucine metabolism regulates mTORC1

Weekes lab (Cell Host Microbe 2018)

Global analysis of antiviral factors degraded by HCMV

Rubinsztein lab (Nature Comm. 2018)

Autophagy control in contact inhibition

Griffiths lab (Nature Immunol. 2018)

Single cell insights into T cell killing capacity 

Larrieu lab (Sci. Signalling 2018)

Transportin-1 targeted in progeria

Siniossoglou lab (Dev. Cell 2018)

A conserved mechanism for membrane phospholipid sensing

Larrieu lab (Nature Comm. 2018)

NAT10 inhibition increases healthspan of HGPS mice

St George-Hyslop lab (Cell 2018)

Phase separation control of FUS in neurodegeneration

Ron lab (J. Biol. Chem. 2018)

Inhibitor sensitivity of the eIF2a phosphatase revisited

Marciniak lab (ASC Nano. 2018)

Measuring microviscosity dynamics inside organelles

Rubinsztein lab (Dev. Cell 2018)

Recycling endosomes as a novel platform for autophagosome formation

Ron and Warren labs (Science 2018)

CryoEM analysis of integrated stress response

Nathan and Lehner labs (EMBO Rep. 2018)

Overlapping E3 ligase function in the ER