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Symeon microscopy image

The mouse lipin 1 is required for lipid droplet biogenesis in differentiating mouse adipocytes. 3T3-L1 cells treated with control siRNA (left panel) or lipin 1 siRNA (right panel). Droplets are labelled in red.
Symeon microscopy image
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A unique partnership between basic and clinical research, aiming to understand the cellular basis of disease

 

 

 

 

 

New publications

 

Ron lab (Cell 2017)

Chaperone control of the unfolded protein response.

 

Ron and Read labs (eLife 2017)

AMPylation inactivation switch for ER chaperone.

 

Robinson and Owen labs (JCB 2017)

Adaptor control of acidic cluster protein sorting.

 

Weekes lab (Cell Rep. 2017)

Dynamic organellar maps in primary neurons.

 

Lehner lab (Nature 2017)

Control of anti-tumour immunity.

 

Buss lab (Cell Rep. 2017)

Myosin VI organization of signalling endosomes.

 

Read and Deane labs (Nature Comm. 2017)

Structural insights into Hunter syndrome.

 

Lehner lab (Nature Genetics 2017)

MORC2 in epigenetic silencing by HUSH complex.

 

Rubinsztein lab (Nature 2017)

PolyQ protein control of autophagy.