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Symeon schematic

Control of lipid partitioning by the conserved yeast lipin Pah1. Loss of Pah1 results in de-repressed nuclear/ER membrane proliferation (arrows, left panel). Conversely, constitutive activation of Pah1 results in lipid droplet accumulation (arrows, right panel).
Symeon schematic
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A unique partnership between basic and clinical research, aiming to understand the cellular basis of disease






New publications

 

Robinson and Owen labs (JCB 2017)

Adaptor control of acidic cluster protein sorting.

 

Weekes lab (Cell Rep. 2017)

Dynamic organellar maps in primary neurons.

 

Ron lab (Mol. Biol. Cell 2017)

IRE1a sensing of membrane aberrancy.

 

Lehner lab (Nature 2017)

Control of anti-tumour immunity.

 

Weekes lab (Cell Rep. 2017)

Temporal proteomics of EBV replication.

 

Read and Deane labs (Nature Comm. 2017)

Structural insights into Hunter syndrome.

 

Lehner lab (Nature Genetics 2017)

MORC2 in epigenetic silencing by HUSH complex.

 

Rubinsztein lab (Nature 2017)

PolyQ protein control of autophagy.