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RefClus

RefClus

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LICENCE AND CONDITIONS OF USE

PLEASE READ THIS SOFTWARE LICENCE AGREEMENT (”LICENCE”) CAREFULLY BEFORE USING THE SOFTWARE. BY DOWNLOADING AND USING THE SOFTWARE, YOU ARE AGREEING TO BE BOUND BY THE TERMS OF THIS LICENCE. IF YOU DO NOT AGREE TO THE TERMS OF THIS LICENCE, YOU SHALL CEASE ALL USE OF THE SOFTWARE AND DESTROY ALL COPIES, FULL OR PARTIAL, FROM ALL MEDIA.

1. Permissions.

This software is free and licensed only for academic use and may not be used in whole or in part for commercial purposes. You may not rent, lease, redistribute, or sublicense the software. You may, however, copy the software from any media to any media subject to a complete transfer of all files in their original state, including this licence.

2. Disclaimer.

YOU EXPRESSLY ACKNOWLEDGE AND AGREE THAT USE OF THE SOFTWARE IS AT YOUR SOLE RISK AND THAT THE ENTIRE RISK AS TO THE SATISFACTORY QUALITY, PERFORMANCE, ACCURACY, AND EFFORT IS WITH YOU. THERE IS NO GUARANTEE THAT THE SOFTWARE IS FREE OF ANY ERROR. SHOULD THE SOFTWARE PROVE DEFECTIVE, YOU ASSUME ENTIRE RESPONSIBILITY FOR ALL CONSEQUENCES THEREOF. THE AUTHORS, LABORATORIES, AND UNIVERSITIES ASSUME NO RESPONSIBILITY FOR ANY MISFORTUNE THAT MAY RESULT FROM THE USE OF THIS SOFTWARE.

3. Termination.

This License is effective until terminated. Your rights under this Licence will terminate automatically without notice should you fail to comply with any term(s) detailed herewith. Upon the termination of this Licence, you shall cease all use of the software and destroy all copies, full or partial, from all media.

I agree to the terms and conditions of this licence,

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New publications

Rubinsztein lab (Cell Reports, 2020)
mTORC2 Assembly Is Regulated by USP9X-Mediated Deubiquitination of RICTOR

Ron lab (eLife, 2020)
Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes

Ron lab in collaboration with the Ito lab, RIKEN (Molecular Cell, 2020)
ISRIB blunts the Integrated Stress Response by allosterically antagonising the inhibitory effect of phosphorylated eIF2 on eIF2B

Raymond and Reid labs (American Journal of Human Genetics, 2020)
De Novo VPS4A Mutations Cause Multisystem Disease with Abnormal Neurodevelopment

Rayner lab (Nature, 2020)
Red blood cell tension protects against severe malaria in the Dantu blood group

Maxwell lab (Nature Immunology, 2020)
Dynamic regulation of hypoxia-inducible factor-1α activity is essential for normal B cell development

Weekes lab (PNAS, 2020)
Human cytomegalovirus protein pUL36: A dual cell death pathway inhibitor

Woods lab (Cell Reports, 2020)
Human Labor Pain Is Influenced by the Voltage-Gated Potassium Channel KV6.4 Subunit

Deane lab (Nature Communications, 2020)
The receptor PTPRU is a redox sensitive pseudophosphatase

Rubinsztein lab (Nature Communications, 2020)
Leucine regulates autophagy via acetylation of the mTORC1 component raptor

Rubinsztein lab in collaboration with the Goldberg lab, Harvard (PNAS, 2020)
cGMP via PKG activates 26S proteasomes and enhances degradation of proteins, including ones that cause neurodegenerative diseases

Griffiths lab (eLife, 2020)
Stimulation strength controls the rate of initiation but not the molecular organization of TCR-induced signalling

Buss lab (Journal of Cell Science, 2020)
OPTN recruitment to a Golgi-proximal compartment regulates immune signalling and cytokine secretion

Rubinsztein lab (Developmental Cell, 2020)
A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy

Buss lab (Biology of Reproduction, 2020)
Myosin VI maintains the actin-dependent organization of the tubulobulbar complexes required for endocytosis during mouse spermiogenesis

Weekes lab (Scientific Reports, 2020)
Comprehensive cell surface proteomics defines markers of classical, intermediate and non-classical monocytes

Buss lab (Traffic, 2020)
Ultrastructural insights into pathogen clearance by autophagy

Read lab (Acta Crystallographica Section D, 2020)
Measuring and Using Information Gained by Observing Diffraction Data

Read lab (Acta Crystallographica Section D, 2020)
Factors influencing estimates of coordinate error for molecular replacement