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Cambridge Institute for Medical Research

 

Professor Matthew Seaman

The molecular mechanisms of endosome-to-Golgi retrieval

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Professor David Ron MD, FMedSci, FRS

Protein folding homeostasis in the endoplasmic reticulum

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Professor Margaret Robinson FRS

Coated vesicle adaptors

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Professor David Owen

Structural biology of transport vesicle and organelle biogenesis

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Professor Paul Luzio

Membrane traffic in the late endocytic pathway

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Dr Delphine Larrieu

Reversing nuclear envelope dysfunction in premature ageing syndromes

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One crucial part of the cell is a structure called the nuclear envelope (NE), surrounding the cell nucleus – home to our DNA. The NE is crucial for maintaining nuclear architecture and cell function.
Dysfunction of the NE leads to various human diseases, including premature ageing syndromes called progeria. Unfortunately, there is no current cure for these diseases, and the available therapies mainly act by improving the symptoms of these patients.

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Dr David Gershlick

Characterising the secretory pathway machinery 

 

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Strategic CIMR themes: Membrane Trafficking, Organelle Biology, Rare Genetic Diseases

Funding: Wellcome Trust, Royal Society

Research Group Members: Jessica Eden, Marie Pereira, Daniele Stalder

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Professor Julian Rayner

The molecular mechanisms of malaria infection

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Professor Folma Buss

Myosin motor proteins in health and disease

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