We aim to create an inspiring environment in which outstanding scientists can excel. By providing state-of-the-art core facilities and support for our researchers, we foster new collaborations that spark discoveries about fundamental cellular processes and their relevance in disease.
In FASEB Journal, the Marciniak lab reveal that accumulation of mutant α1-antitrypsin polymers, implicated in liver disease, leads to fragmentation of the ER, but does not prevent SNARE-mediated vesicular transport.
Warmest congratulations to Peter Ratcliffe, William Kaelin, and Gregg Semenza, whose discovery of oxygen sensing as an essential physiological process has received this year's Lasker Basic Medical Research award. We are particularly proud of the recognized contributions to this work made by Patrick Maxwell in the lab of Peter Ratcliffe.