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Cambridge Institute for Medical Research

Department A-Z

Our strategy

We aim to create an inspiring environment in which outstanding scientists can excel. By providing state-of-the-art core facilities and support for our researchers, we foster new collaborations that spark discoveries about fundamental cellular processes and their relevance in disease.

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Research advances

In Cell Metabolism, the Nathan lab use a forward genetic screen in human cells to reveal a novel metabolic pathway by which hypoxia-inducible factor (HIF) stability is controlled in aerobic conditions, highlighting interplay between oxygen and metabolic sensing.

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Research advances

The Robinson lab report in eLife that the antiviral protein tetherin also attaches secreted exosomes to the cell surface, providing a potential means of control over exosome-mediated communication.

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Potential haemophilia treatment

A new strategy that might be used to treat haemophilia, arising from a collaboration between the Huntington lab and Trevor Baglin at Addenbrooke's Hospital, is now being progressed by the start-up company ApcinteX.

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New approaches to type 1 diabetes

Clinical research led by Frank Waldron-Lynch suggests that limiting autoimmune damage against insulin-producing cells may be an effective approach to treating type 1 diabetes.

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Dementia: catching the memory thief

A new video highlighting Cambridge research into dementia, including David Rubinsztein and Peter St George-Hyslop.

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A unique partnership between basic and clinical research, aiming to understand the cellular basis of disease






New publications

 

Huntington lab (Blood 2016)

Engineered serpins for rescue of thrombin generation.

 

Lehner lab (eLife 2016)

Vif targeting of PP2A in HIV infection.

 

Nathan lab (Cell Met. 2016)

Coordinated oxygen and metabolic sensing.

 

Lehner lab (Cell Rep. 2016)

ATF7IP is a key effector of the HUSH complex.

 

Robinson lab (eLife 2016)

Tetherin as an exosomal tether.

 

Marciniak lab (FASEB J. 2016)

ER transport after fragmentation.