We aim to create an inspiring environment in which outstanding scientists can excel. By providing state-of-the-art core facilities and support for our researchers, we foster new collaborations that spark discoveries about fundamental cellular processes and their relevance in disease.
The Seaman lab reveal in Cell Reports the findings of their genome-wide siRNA screen for regulators of endosome-to-Golgi retrieval, a process implicated in neurodegenerative disease. Among >80 hits, they find a new role for three multipass membrane-spanning proteins.
The Rubinsztein lab report in Nature Communications that the endocytic adaptor protein PICALM, previously associated with Alzheimer's disease, modulates autophagy and clearance of the microtubule-associated protein tau both in vitro and in vivo, as well as tau-mediated toxicity in zebrafish.
Congratulations to Eoin McKinney in the Smith lab, who has been awarded a Wellcome Trust Intermediate Clinical Fellowship and a Wellcome-Beit Prize Fellowship, the latter of which recognizes just four outstanding biomedical researchers each year.
CIMR PI Jim Huntington and the team at XO1 Ltd received a Cambridge News Top Innovation award this week for the development of a new synthetic antibody that could prevent heart attacks and strokes without causing bleeding.
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