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Cambridge Institute for Medical Research

Department A-Z

Our strategy

We aim to create an inspiring environment in which outstanding scientists can excel. By providing state-of-the-art core facilities and support for our researchers, we foster new collaborations that spark discoveries about fundamental cellular processes and their relevance in disease.

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Research advances

The St George-Hyslop lab have shown in Neuron that disease mutations in the RNA-binding protein FUS, linked to amyotrophic lateral sclerosis and frontotemporal dementia, lead to formation of irreversible hydrogel assemblies that disrupt neuronal protein synthesis.

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Research advances

In Nature Structural & Molecular Biology, the Warren lab have used single particle cryo-electron microscopy to reveal a fundamental and conserved step in ribosome maturation, which is disrupted in both inherited and sporadic forms of leukaemia.

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Apply now for MRC PhD studentships

Six fully funded MRC PhD projects are being offered by CIMR supervisors, commencing in October 2016. Apply by December 2nd!

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Cambridge Enterprise video

Jim Huntington opens a new video highlighting the aims and advances of Cambridge Enterprise, the commercialization arm of Cambridge University.

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Biochemical Society poster prize

Congratulations to Guy Pearson (Reid lab), winner of the best poster prize at the Biochemical Society meeting: Organelle Crosstalk in Membrane Dynamics and Cell Signalling.

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News feature

Insights into neurodegeneration highlight the importance of considering mechanisms of disease as physical, as well as biological, processes.

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A unique partnership between basic and clinical research, aiming to understand the cellular basis of disease

New publications

Buss lab (Plos Path. 2015)

Myosin VI in Salmonella autophagy.

Ron lab (J. Cell Biol. 2015)

A lumenal source of ER hydrogen peroxide.

Lehner lab (Nature Comm. 2015)

Non-proteolytic ubiquitin role in mRNA deadenylation.


Ron lab (eLife 2015)

Control of BiP activity by oligomerization.

Lehner lab (Cell Host Microbe 2015)

HIV targets host immunometabolism.

Rubinsztein lab (Nature Comm. 2015)

Autophagy promoted by Annexin A2.

Smith lab (Nature 2015)

T cell exhaustion and clinical outcome.

Lehner lab (Science 2015)

HUSH complex maintains transcriptional silencing.