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Cambridge Institute for Medical Research

Department A-Z

Our strategy

We aim to create an inspiring environment in which outstanding scientists can excel. By providing state-of-the-art core facilities and support for our researchers, we foster new collaborations that spark discoveries about fundamental cellular processes and their relevance in disease.

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Research advances

In FASEB Journal, the Marciniak lab reveal that accumulation of mutant α1-antitrypsin polymers, implicated in liver disease, leads to fragmentation of the ER, but does not prevent SNARE-mediated vesicular transport.

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Research advances

The Robinson lab report in eLife that the antiviral protein tetherin also attaches secreted exosomes to the cell surface, providing a potential means of control over exosome-mediated communication.

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Dementia: catching the memory thief

A new video highlighting Cambridge research into dementia, including David Rubinsztein and Peter St George-Hyslop.

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Lasker award

Warmest congratulations to Peter Ratcliffe, William Kaelin, and Gregg Semenza, whose discovery of oxygen sensing as an essential physiological process has received this year's Lasker Basic Medical Research award. We are particularly proud of the recognized contributions to this work made by Patrick Maxwell in the lab of Peter Ratcliffe.

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Postgraduate open day

An opportunity to meet with academics and current students at this new University event on November 2nd.

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A unique partnership between basic and clinical research, aiming to understand the cellular basis of disease

New publications


Robinson lab (eLife 2016)

Tetherin as an exosomal tether.


Marciniak lab (FASEB J. 2016)

ER transport after fragmentation.


Luzio lab (Curr. Biol. 2016)

Re-evaluating the lysosome regeneration cycle.


Lehner lab (Traffic 2016)

Trafficking control of tetherin.


Rubinsztein lab (Nature Comm. 2016)

Autophagy-lysosome dysfunction in Parkinson's disease.


Lehner lab (Nature Comm. 2016)

Forward-genetic screens of mammalian ER-associated degradation.