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Cambridge Institute for Medical Research

Department A-Z

Our strategy

CIMR is a unique partnership between basic and clinical research, aiming to understand the cellular basis of disease. Our goal is to create an inspiring environment in which outstanding scientists can excel. By providing state-of-the-art core facilities and support for our researchers, we foster new collaborations that spark discoveries about fundamental cellular processes and their relevance in disease.

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Research advances

In Nature Communications, the Robinson lab discover that WDR11 is a regulator of vesicle tethering during endosome to Golgi transport, facilitating golgin-mediated capture of vesicles.

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Research advances

Reporting in Dev. Cell, the Buss lab has uncovered a new role for the actin-based myosin VI motor in ‘caging’ damaged mitochondria for their efficient removal by mitophagy.

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Group leader opportunity

The CIMR is seeking to recruit one or more principal investigators, and we are particularly interested to hear from early career researchers.

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Cambridge Science Festival 2018

Come along to our drop-in weekend events (March 17, 18 and 25th) and learn about how we use microscopes to light up cells! Book to hear Professor Geoff Woods on the importance of pain sensing (March 21st).

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Policy internship

Congratulations to Katharina Strege (PhD student in Griffiths lab and Adams lab, Sanger Institute), who has been selected for an RCUK policy internship at the Royal Society this spring.

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A unique partnership between basic and clinical research, aiming to understand the cellular basis of disease

 

 

 

 

 

New publications

 

Robinson lab (Nature Comm. 2018)

WDR11 in Golgi vesicle tethering.

 

Buss and Nathan labs (Dev. Cell 2018)

Myosin VI-driven actin cages in mitophagy.

 

Deane lab (Nature Comm 2018)

Structural insights into GALC-SapA sphingolipid processing.

 

Ron lab (Cell 2017)

Chaperone control of the unfolded protein response.

 

Ron and Read labs (eLife 2017)

AMPylation inactivation switch for ER chaperone.

 

Robinson and Owen labs (JCB 2017)

Adaptor control of acidic cluster protein sorting.

 

Weekes lab (Cell Rep. 2017)

Dynamic organellar maps in primary neurons.

 

Lehner lab (Nature 2017)

Control of anti-tumour immunity.

 

Buss lab (Cell Rep. 2017)

Myosin VI organization of signalling endosomes.