Cytotoxic T lymphocytes (CTLs) recognise and destroy cells which are infected with viruses or are cancerous. This latter property puts them at the heart of new immunotherapies transforming cancer...
Like many key biological pathways, the Integrated Stress Response (ISR) is carefully regulated. A known molecular trigger for the ISR is the stress-induced phosphorylation of the α-subunit of...
There have been some major developments in computational tools to predict the 3D structures of proteins. Nature recently published the details of AlphaFold2 , the machine-learning product of Google...
Ribosomopathies such as Shwachman-Diamond syndrome (SDS) are rare diseases caused by defects in ribosome assembly. A new international study co-led by Prof. Alan Warren (CIMR) and Prof. Patrick Revy...
BiP is a molecular chaperone of the endoplasmic reticulum (ER), playing a tightly-regulated role in protein folding and the Unfolded Protein Response. Under normal conditions, a substantial fraction...
With over 70 postdocs at CIMR, we support Postdoc Appreciation Week (September 20th – 24th) and want to acknowledge the great work postdocs do as part of the bedrock of the global science effort –...
Experience Postgrad Life Sciences is a residential summer internship programme at Cambridge for undergraduate students of biological / biomedical science subjects who may not otherwise be able to...
Professor Stefan Marciniak is a research group leader at CIMR and an honorary consultant respiratory physician at both Cambridge University Hospitals NHS Foundation Trust and Royal Papworth. He will...
