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Cambridge Institute for Medical Research

Department A-Z

Our strategy

CIMR is a unique partnership between basic and clinical research, aiming to understand the cellular basis of disease. Our goal is to create an inspiring environment in which outstanding scientists can excel. By providing state-of-the-art core facilities and support for our researchers, we foster new collaborations that spark discoveries about fundamental cellular processes and their relevance in disease.

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Research advances

The St George-Hyslop group has collaborated with researchers in Departments of Chemistry, Chemical Engineering and PDN in a Cell study to determine the modifications of the RNA-binding protein FUS that regulate its phase separation.

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Research advances

In Dev. Cell, the Rubinsztein lab discover that recycling endosomes form a primary platform for autophagosome formation, through a novel interaction between RAB11A and WIPI2.

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Roger de Spoelberch Prize

Many congratulations to David Rubinsztein, who has been awarded the 2017 Roger de Spoelberch prize for his contributions to neurodegeneration research.

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Cambridge Science Festival 2018

Thank you all for coming to our Festival events and helping us build cells!

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Pilkington Prize

Many congratulations to Folma Buss, CIMR Director of Graduate Studies, who has been awarded a 2018 Pilkington Prize for excellence in teaching.

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A unique partnership between basic and clinical research, aiming to understand the cellular basis of disease

 

 

 

 

 

New publications

 

St George-Hyslop lab (Cell 2018)

Phase separation control of FUS in neurodegeneration.

 

Ron lab (J. Biol. Chem. 2018)

Inhibitor sensitivity of the eIF2a phosphatase revisited.

 

Marciniak lab (ASC Nano. 2018)

Measuring microviscosity dynamics inside organelles.

 

Rubinsztein lab (Dev. Cell 2018)

Recycling endosomes as a novel platform for autophagosome formation.

 

Ron and Warren labs (Science 2018)

CryoEM analysis of integrated stress response.

 

Nathan and Lehner labs (EMBO Rep. 2018)

Overlapping E3 ligase function in the ER.

 

Robinson lab (PLoS Biol. 2018)

AP-5 in endosome-to-Golgi transport.

 

Robinson lab (Nature Comm. 2018)

WDR11 in Golgi vesicle tethering.

 

Buss lab (EMBO Rep. 2018)

The myosin VI interactome.

 

Buss and Nathan labs (Dev. Cell 2018)

Myosin VI-driven actin cages in mitophagy.

 

Ron lab (Cell 2017)

Chaperone control of the unfolded protein response.