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Cambridge Institute for Medical Research

Department A-Z

Our strategy

CIMR is a unique partnership between basic and clinical research, aiming to understand the cellular basis of disease. Our goal is to create an inspiring environment in which outstanding scientists can excel. By providing state-of-the-art core facilities and support for our researchers, we foster new collaborations that spark discoveries about fundamental cellular processes and their relevance in disease.

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Research advances

The Siniossoglou group has collaborated with the Savage group (Institute of Metabolic Sciences) to elucidate a conserved biophysical mechanism for phospholipid sensing by the PCYT1 enzyme at the inner nuclear membrane.

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Research advances

The St George-Hyslop group has collaborated with researchers in Departments of Chemistry, Chemical Engineering and PDN in a Cell study to determine the modifications of the RNA-binding protein FUS that regulate its phase separation.

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2018 Academy of Medical Sciences Fellows

We are delighted that Jim Huntington has been elected as a Fellow of the Academy of Medical Sciences.

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Roger de Spoelberch Prize

Many congratulations to David Rubinsztein, who has been awarded the 2017 Roger de Spoelberch prize for his contributions to neurodegeneration research.

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Cambridge Science Festival 2018

Thank you all for coming to our Festival events and helping us build cells!

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A unique partnership between basic and clinical research, aiming to understand the cellular basis of disease

 

 

 

 

 

New publications

 

Siniossoglou lab (Dev. Cell 2018)

A conserved mechanism for membrane phospholipid sensing.

 

Larrieu lab (Nature Comm. 2018)

NAT10 inhibition increases healthspan of HGPS mice.

 

St George-Hyslop lab (Cell 2018)

Phase separation control of FUS in neurodegeneration.

 

Ron lab (J. Biol. Chem. 2018)

Inhibitor sensitivity of the eIF2a phosphatase revisited.

 

Marciniak lab (ASC Nano. 2018)

Measuring microviscosity dynamics inside organelles.

 

Rubinsztein lab (Dev. Cell 2018)

Recycling endosomes as a novel platform for autophagosome formation.

 

Ron and Warren labs (Science 2018)

CryoEM analysis of integrated stress response.

 

Nathan and Lehner labs (EMBO Rep. 2018)

Overlapping E3 ligase function in the ER.

 

Robinson lab (PLoS Biol. 2018)

AP-5 in endosome-to-Golgi transport.

 

Robinson lab (Nature Comm. 2018)

WDR11 in Golgi vesicle tethering.

 

Buss lab (EMBO Rep. 2018)

The myosin VI interactome.