Publications

2025

Buss lab (Journal of Cell Science December 2025)

The MYO1F interactome reveals ASAP1, CD2AP and SH3KBP1 as novel adaptor proteins in podosomes and phagosomes

Ron lab (Molecular Cell October 2025)

A structural basis for chaperone repression of stress signaling from the endoplasmic reticulum

Rubinsztein lab (Cell Reports September 2025)

Coordination of autophagosome closure and release by the Alzheimer’s disease-associated protein BIN1

Warren lab (Sci Adv July 2025)

PELP1 coordinates the modular assembly and enzymatic activity of the rixosome complex

Salje lab (Nature Communications June 2025)

The intracellular bacterium Orientiatsutsugamushi uses the autotransporterScaC to activate BICD adaptors fordynein-based motility

Deane lab (PLoS Biology July 2025)

Plasma membrane remodeling in GM2 gangliosidoses drives synaptic dysfunction | PLOS Biology

Deane lab (Nature Communications July 2025)

Conformational dynamics and membrane insertion mechanism of B4GALNT1 in ganglioside synthesis

Salje lab (PLoS Pathog June 2025)

Comparative virulence analysis of seven diverse strains of Orientia tsutsugamushi reveals a multifaceted and complex interplay of virulence factors responsible for disease

Rubinsztein lab (Developmental Cell June 2025)

Transferrin receptor controls both autophagosome formation and closure via phosphatidylinositol 3-phosphate synthesis

Gammons lab (Nature Communications May 2025)

Wnt signalosome assembly is governed by conformational flexibility of Axin and by the AP2 clathrin adaptor

Rubinsztein lab (Neuron April 2025)

Alpha-synuclein mutations mislocalise cytoplasmic p300 compromising autophagy, which is rescued by ACLY inhibition.

St George-Hyslop/ Nixon-Abell lab (Nature Communications March 2025)

ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes

Marciniak lab (Nature Genetics March 2025)

Selection for somatic escape variants in SERPINA1 in the liver of patients with alpha-1 antitrypsin deficiency | Nature Genetics

Weekes lab (Cell Reports Feb 2025)

Spatial proteomics identifies a CRTC-dependent viral signaling pathway that stimulates production of interleukin-11

Rayner lab (Science Feb 2025)

Supersaturation mutagenesis reveals adaptive rewiring of essential genes among malaria parasites

Dickens/ Marciniak lab (EMBO Feb 2025)

A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease

Siniossoglou lab (EMBO J 2025)

Partitioning of fatty acids between membrane and storage lipids controls ER membrane expansion