CIMR vacancies on www.jobs.cam.ac.uk

We are seeking an enthusiastic, motivated individual for a position in the group of Professor Mike Weekes, Department of Medicine in the Cambridge Institute for Medical Research at the Cambridge Biomedical Campus. You will join an exciting research programme investigating critical host factors influencing the pathogenesis of Monkepox Virus. This post will involve the use of cutting edge proteomic and biochemical techniques to identify cellular targets of Monkeypox, and determine how they influence viral replication.

This position is available for an immediate appointment. Candidates must either have a PhD in a relevant biological subject, or have submitted or about to submit their PhD thesis. Candidates must also have demonstrable expertise in virology, cell biology and/or molecular biology. Additional training in proteomics will be provided. Relevant post-doctoral experience is desirable. High quality peer-reviewed publications and a keen interest in viral/cellular regulation are essential.

If you have an excellent background in biological sciences, are prepared to face intellectual challenges and wish to develop your scientific skills, we would like to hear from you. Applicants should have outstanding organisation and communication skills, and work well as part of a team.

Appointment at Research Associate level is dependent on having a PhD including those who have submitted but not yet received their PhD. Where a PhD has yet to be, awarded appointment will initially be made at research assistant and amended to research associate when the PhD is awarded (PhD needs to be awarded within 6 months of the start date)

Salary Ranges:

Research Assistant: £32,546 - £35,116

Research Associate: £37,174 - £45,413

The Cambridge Institute for Medical Research (CIMR) is located on the Cambridge Biomedical Campus and it is a collaborative institute at the interface between fundamental research and the clinic, with a mission to determine the molecular mechanisms of disease in order to advance human health.

Funding for this position is for 3 years in the first instance with a start date as soon as possible.

For recent related publications, see below:

Nightingale et al. (2018) Cell Host & Microbe doi: 10.1016/j.chom.2018.07.011 Nobre et al. (2019) eLife. doi: 10.7554/eLife.49894 Fletcher-Etherington et al. (2020) PNAS. doi: 10.1073/pnas.2001887117 Albarnaz et al. (2023) Nature Communications. doi: 10.1038/s41467-023-43299-8 Ravenhill et al. (2025) Cell Reports. doi: 10.1016/j.celrep.2025.115263

Informal enquiries to Professor Mike Weekes: mpw1001@cam.ac.uk

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Closing date: Sunday 18th May 2025

Interview Date: Tuesday 3rd June 2025

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

For information about how your personal data is used as an applicant, please see the section on Applicant Data (https://www.hr.admin.cam.ac.uk/hr-staff/hr-data/applicant-data) on our HR web pages.

Please quote reference SC45751 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Cambridge Institute for Medical Research (CIMR)

An exciting opportunity has arisen for a Scientific Support Technician (SST) to join the CIMR Laboratory Management Team. Part of a wider Research Support Team, the role works closely with another Scientific Support Technician and two Laboratory Support Technicians. This role is ideal for someone looking to develop their career in Laboratory Management.

As the Senior Support Technician, you will provide support and assistance for the communal laboratory facilities. These facilities include Tissue Culture labs, Containment Level 2/Blood Handling labs, Radioactive Tissue Culture, Core Equipment rooms (including centrifuges, spectrometers, orbital incubators, PCR machines, gel documentation systems, etc.), cold rooms, and dark rooms.

Key Responsibilities:

• Support and Assistance: Provide day-to-day support for communal laboratory facilities

• Equipment Management: Negotiate discounts on consumables, arrange maintenance and repairs of laboratory equipment

• Training: Train new starters and students in the use of core equipment such as ultra-centrifuges and carry out first day building inductions for new employees/students/visitors

• Management: Manage booking systems and cleaning rotas for Tissue Culture Labs and other core areas

• Cost Recovery: Calculate cost recovery charges to the Research Groups for core facilities

• Line Management: the role will manage a Grade 3 Support Technician

• Teamwork: You will work closely with a second Grade 6 SST, and two Grade 3 Support Technicians and are expected to manage your own workload in conjunction with your fellow team members

For Grade 6 appointments, the successful applicant will be qualified to HNC level in Biological Sciences or equivalent and have substantial experience in a research laboratory environment as well as experience with a wide range of laboratory equipment and purchasing consumables. The understanding and experience of laboratory safety guidelines, with significant knowledge of Biological and GM Safety is highly desirable, with the successful candidate expected to be appointed as Biological Safety Officer for CIMR.

CIMR actively seeks to develop and train staff for their future and has had significant success in meeting this aim. Less experienced applicants with similar qualifications and identifiable potential for development are encouraged to apply. In such cases, the appointment is likely to be made initially at Grade 5, with the prospect of promotion to Grade 6 once full performance of duties is achieved.

Salary Range:

£33,482 - £39,355 (Grade 6)

£30,805 - 35,116 (Grade 5)

This is a full-time (36.5 hours/week), permanent role working Monday to Friday.

Join us at the Cambridge Institute for Medical Research and contribute to ground breaking research in a supportive and dynamic environment

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Closing date: Sunday 18th May 2025

Interview Date: Expected to be week starting 2nd June 2025

Please ensure that you outline how you match the criteria for the post and why you are applying for this role on the online application form.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

For information about how your personal data is used as an applicant, please see the section on Applicant Data (https://www.hr.admin.cam.ac.uk/hr-staff/hr-data/applicant-data) on our HR web pages.

Please quote reference SA45757 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

We are looking to appoint a highly qualified and motivated individual with experience in mass spectrometry to the proteomics facility at the Cambridge Institute for Medical Research (CIMR https://www.cimr.cam.ac.uk ), University of Cambridge.

The proteomics facility offers comprehensive quantitative proteomic analysis for a wide range of sample types to academic users within CIMR, wider Cambridge University departments, as well as to academic laboratories more broadly across the UK. The facility is currently equipped with two Thermo Orbitrap analysers: a QExactive Plus and a Fusion Lumos, and we are planning to acquire a Bruker timsTOF HT in the near future.

This role involves managing aspects of the facility, including its finances and external engagement (e.g. interactions with biotech and pharmaceutical companies), as well as providing support and advice to academic users, carrying out sample and data analysis, and maintaining the facility's instruments.

You should have a PhD with extensive experience in a proteomics/mass spectrometry laboratory, outstanding organisation and communication skills, and should work well as part of a team. In-depth knowledge of and extensive hands-on experience in the following areas is essential:

• Analysis of proteins and peptides by LC-MS/MS;

• Operation of the Orbitrap and other nanoflow-inlet-based instrument platforms and quantitative proteomics strategies;

• Experience with bioinformatics analysis and software for protein identification and validation as well as protein quantification.

Funding for this position is for 3 years in the first instance with a start date as soon as possible.

CIMR's mission is to determine the molecular mechanisms of disease in order to advance human health. Major research interests in the CIMR include rare genetic disease, neurological disease, and intracellular infection.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Closing date: 18th May 2025

Interview Date: to be held end of May / beginning of June 2025

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager

For information about how your personal data is used as an applicant, please see the section on Applicant Data (https://www.hr.admin.cam.ac.uk/hr-staff/hr-data/applicant-data) on our HR web pages.

Please quote reference SA45725 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

An opportunity has arisen to join the Accounts & Purchasing team in the Cambridge Institute for Medical Research (CIMR). This is a varied role that includes placing purchase orders, processing accounts payable using our new invoice automation system, some accounts receivable work, checking and processing expense claims and dealing with queries from colleagues and suppliers. You will be able to support other team members in providing a first-class accounts service to the Institute's scientists, which will include covering their tasks during periods of leave.

You should be educated to GCSE Grade C (or equivalent) in English and Maths, possess excellent interpersonal skills and have the ability to maintain accuracy when working to tight deadlines. An AAT Foundation/Introductory qualification would be an advantage.

CIMR is located on the Cambridge Biomedical Campus and forms part of the University of Cambridge School of Clinical Medicine. We provide modern laboratory accommodation and state of the art research facilities for the Institute's researchers who study the molecular mechanisms of disease. The researchers are all supported by an administration team who cover HR, Finance, IT, Building Services and Laboratory Management to ensure that the Institute runs smoothly.

This is a full-time role (36.5 hours per week) working Monday to Friday.

The position is available immediately.

Informal enquiries are welcomed and should be directed to Aga Lanucha, Accounts & Purchasing Supervisor al512@cam.ac.uk

If you have any queries regarding the application process, please contact the Clinical School HR Team on cshrstaffhub@admin.cam.ac.uk

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Please ensure that you outline how you match the criteria for the post and why you are applying for this role on the online application form.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Closing date: 27th April 2025

Interview date: 8th May 2025

Please quote reference SA45547 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

We are seeking an enthusiastic and skilled Post-doctoral Researcher to join the Nixon-Abell Laboratory at the Cambridge Institute for Medical Research. Our work sits at the interface between cell biology and molecular neuroscience. We employ integrated experimental approaches, combining cutting-edge microscopy, biochemistry, omics, and iPSC-derived cell models to understand organelle interactions and dynamics in neurons.

This Wellcome Trust funded project aims to draw fundamental links between organellar communication pathways and neuronal function. Specifically, the post-holder will focus on understanding how sites of direct physical interaction between organelles (membrane contact sites) coordinate the intracellular distribution of lipids in neurons. The candidate will form part of a vibrant and interdisciplinary team focussed on producing rigorous, innovative and impactful research. This role will also offer various career development opportunities to support the candidate's professional progression.

All applicants must hold a PhD in a relevant field and have research experience in mechanistic cell biology. Prior post-doctoral research experience is highly desirable. A background in lipid biology is required and technical experience in one or more of the following would be beneficial: endomembrane biology assays, lipidomics/metaboolomics/proteomics, in vitro reconstitution systems.

The Cambridge Institute for Medical Research (CIMR) is located on the Cambridge Biomedical Campus and it is a collaborative institute at the interface between fundamental research and the clinic, with a mission to determine the molecular mechanisms of disease in order to advance human health.

The successful applicant will be expected to work independently and collaboratively as part of a diverse team. This full-time fixed-term post is funded by the Wellcome Trust for up to 3 years. This position is graded on the University's Grade 7 scale, for which the salary range is £36,924 - £45,163 per annum. The starting salary offered will be based on qualification and relevant skills acquired and will be determined by the funding available.

For informal enquiries please contact Dr Jonathon Nixon-Abell (jjn36@cam.ac.uk).

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Closing date: 7th March 2025

Interviews will be held in March 2025

If you have any queries regarding the application process please contact the Clinical School HR Team via email cshrstaffhub@admin.cam.ac.uk.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including e-mail address and phone number, one of which must be your most recent line manager.

For information about how your personal data is used as an applicant, please see the section on Applicant Data (https://www.hr.admin.cam.ac.uk/hr-staff/hr-data/applicant-data )on our HR web pages.

Please quote reference SD42428 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

The Salje lab in the Cambridge Institute for Medical Research is seeking a talented and motivated Computational Biologist to join the team and work on genomic analysis and comparative genomics of Rickettsial bacterial genomes. The lab group investigates the host-pathogen cell biology of Rickettsial diseases with a particular focus on Orientia tsutsugamushi, the causative agent of scrub typhus.

This role will primarily focus on analysing genomic data generated using nanopore sequencing technologies to provide insights into bacterial evolution, diversity, and function.

You should have (or will have by September 2025) a BSc in the field of biological sciences and a Masters or integrated Masters degree in Computational Biology, Bioinformatics, Genomics, or a related field.

You will be expected to work within a highly interactive group, to have a friendly and collegiate outlook, to have good written and verbal communications skills, to be well-organised and have the ability to work calmly to meet deadlines.

There are funds available for one year from 1st October 2025 for this project.

Cambridge Institute for Medical Research is a centre of excellence that has a strong focus on understanding the molecular mechanisms of disease, with the aim of translating basic discoveries to clinically meaningful therapies. It is known for its positive research culture.

Informal enquiries are welcomed and should be directed to: Dr Jeanne Salje Email: jss53@cam.ac.uk

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Closing date: 25th February 2025

Interviews will be held in March 2025

If you have any queries regarding the application process please contact the Clinical School HR Team via email cshrstaffhub@admin.cam.ac.uk.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including e-mail address and phone number, one of which must be your most recent line manager.

For information about how your personal data is used as an applicant, please see the section on Applicant Data (https://www.hr.admin.cam.ac.uk/hr-staff/hr-data/applicant-data )on our HR web pages.

Please quote reference SH44853 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

The ALBORADA Drug Discovery Institute (ADDI), part of the University of Cambridge CIMR Division of Translational Medicine (http://cambridge-ddi.alzheimersresearchuk.org/), is seeking a biologist with a background in neurodegeneration. The ALBORADA DDI is part of a network of world-class Drug Discovery Institutes, funded by Alzheimer's Research UK, forming the Alzheimer's Research UK Drug Discovery Alliance. The work of the DDI at Cambridge is aimed at validating new drug targets and identifying potential new drugs for the treatment of Alzheimer's disease as well as other forms of neurodegeneration.

The successful candidate will be a member of our Cell and Molecular Biology Team and will be responsible for designing and performing studies to validate the link between targets and disease and for carrying out studies to characterise and assess compounds emerging from our drug discovery programmes. This is a highly collaborative role which involves working alongside colleagues in the screening and in vivo teams and with medicinal and computational chemists to progress projects from target identification through to in vivo proof of concept in rodent models.

The role is primarily lab-based and demands an enthusiastic and proactive mindset, along with a demonstrable ability to troubleshoot and optimise methods and an aptitude for data analysis. Working with chemists and other biologists in a stimulating and collaborative environment with opportunities for training and development, the successful candidate will also be encouraged to contribute to implementing new technologies and processes as well as develop a leading role in their specialist laboratory skillset.

The successful candidate will be required to have the following skills and experience:

• A PhD in Biology with laboratory-based experience, or over 5 years of experience in a relevant industrial environment.
• Experience in neurodegenerative disease research.
• Practical experience with optimising and troubleshooting immunostaining, PCR and basic molecular biology techniques.
• Familiarity with cell-based assays and culture techniques.
• A willingness to provide scientific leadership and supervise junior staff.

Additional desirable attributes would be:

• Experience with isolating and maintaining neuronal and neuroglial cell lines and primary cells, including pluripotent stem cells.
• Knowledge of handling large data sets from image analysis and data analysis software.
• Knowledge of high-content and high-thoughput automation platforms.
• Experience with the drug discovery process.

Fixed-term: The funds for this post are available until 30 April 2026 in the first instance.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Closing Date: 10th February

Informal enquiries are welcomed and should be directed to: Dr Jonathan Clarke Email: jhc30@cam.ac.uk

Please quote reference SA44712 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.